Purity > 90% as determined by SDS-PAGE. MW: 48.6kDa. Full Length of Mature Protein: 18-417aa. N-terminal 6xHis-tagged. Sus scrofa (Pig). Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export (By similarity). Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis.
Size
100ug
Concentration
n/a
Applications
RUO
Other Names
Alternative name (s):CRP55; Calregulin; Endoplasmic reticulum resident protein 60; Short name:ERp60 HACBP