Purity > 90% as determined by SDS-PAGE. MW: 44.7kDa. Full Length: 1-261aa. N-terminal 6xHis-SUMO-tagged. Burkholderia mallei (strain ATCC 23344). Activator for both CDC42 and RAC1 by directly interacting with these Rho GTPases and acting as a guanine nucleotide exchange factor (GEF). This activation results in actin cytoskeleton rearrangements and stimulates membrane ruffling, thus promoting bacterial entry into non-phagocytic cells