An inhibitor of Akt1 and Akt2 with anticancer activity; inhibits Akt1 and Akt2 in a kinase assay, but has no effect on MEK1, JNK1, ERK1, or PBK at 1 μM; increases apoptosis in HCT116 and HT-29 colon cancer cells at 4 μM; inhibits growth of HCT116 cells in vitro; reduces tumor growth in an HCT116 mouse xenograft model at 30 mg/kg; decreases status epilepticus-induced vasogenic edema and reduces increases in eNOS levels in the piriform cortex in rats at 25 μM