Purity ~90% (SDS-PAGE). Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. Inhibits RPS6KA3 activities by retaining it in the cytoplasm. Inhibits both TNFRSF6- and TNFRSF1A-mediated CASP8 activity and apoptosis. Regulates glucose transport by controlling both the content of SLC2A1 glucose transporters on the plasma membrane and the insulin-dependent trafficking of SLC2A4 from the cell interior to the surface. Source: Recombinant protein corresponding to aa1-130 from human PEA15, fused to GST-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~42.0kD AA
Size
10ug, 50ug, 100ug
Concentration
n/a
Applications
n/a
Other Names
15kD phosphoprotein enriched in astrocytes, Phosphoprotein enriched in diabetes