PEA-15, Recombinant Human (Phospho-enriched protein in astrocytes 15kD)
Description
Purity ~90% by SDS-PAGE Purified by immunoaffinity chromatography. Phospho-enriched protein in astrocytes 15kD (PEA-15) is a death effector domain (DED)-containing protein predominantly expressed in the central nervous system, particularly in astrocytes. This protein has been implicated in the regulation of multiple cellular processes including apoptosis, proliferation, glucose transport, adhesion and migration. Increased PEA-15 levels may affect tumorigenesis and cancer progression, thus it is overexpressed in breast cancers and gliomas as well as in type 2 diabetes. Recombinant human PEA-15 , expressed in E. coli and purified by using conventional chromatography. Source: Recombinant human PEA-15, aa1-130, expressed in E. coli AA Sequence: MAEYGTLLQD LTNNITLEDL EQLKSACKED IPSEKSEEIT TGSAWFSFLE SHNKLDKDNL SYIEHIFEIS RRPDLLTMVV DYRTRVLKIS EEDELDTKLT RIPSAKKYKD IIRQPSEEEI IKLAPPPKKA Applications: Suitable for use in ELISA and Western Blot.