Recombinant Human Cation-independent mannose-6-phosphate receptor (MPRI), partial
Description
Purity > 90% as determined by SDS-PAGE. MW: 45.3kDa. Partial: 2328-2491aa. N-terminal GST-tagged. Homo sapiens (Human). Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex.