Purity ~90% (SDS-PAGE). CD37 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms. Source: Recombinant protein corresponding to aa112-241 from human CD37, fused to His-tag at N-terminus, expressed in E.coli. Molecular Weight: ~17.4kD (154aa) Applications: Suitable for use in SDS-PAGE.