| Edit |   |
|---|
| Antigenic Specificity | Claudin 6/CLDN6 |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human |
|---|
| Isotype | n/a |
|---|
| Format | immunogen affinity purified |
|---|
| Size | 100ug (sample available) |
|---|
| Concentration | 500ug/ml. |
|---|
| Applications | WB |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Rabbit IgG polyclonal antibody for Claudin-6(CLDN6) detection. Tested with WB in Human. No cross reactivity with other proteins. Claudin-6 is a protein that in humans is encoded by the CLDN6 gene. It belongs to the group of claudins. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16. |
|---|
| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human Claudin 6(204-220aa APAISRGPSEYPTKNYV). |
|---|
| Other Names | Claudin-6;Skullin;CLDN6;UNQ757/PRO1488; |
|---|
| Gene, Accession # | CLDN6, UniProt: P56747 |
|---|
| Catalog # | PA2020 |
|---|
| Price | |
|---|
| Order / More Info | Claudin 6/CLDN6 Antibody from BOSTER BIO |
|---|
| Product Specific References | n/a |
|---|