Recombinant Human TP53-regulated inhibitor of apoptosis 1 (TRIAP1)
Description
Purity > 90% as determined by SDS-PAGE. MW: 35.8kDa. Full Length: 1-76aa. N-terminal GST-tagged. Homo sapiens (Human). Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane. Likewise, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid (PA) between liposomes (in vitro) and probably functions as a PA transporter across the mitochondrion intermembrane space (in vivo). Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis
Size
100ug
Concentration
n/a
Applications
RUO
Other Names
Protein 15E1.1; WF-1; p53-inducible cell-survival factor