An NSAID and a class IIb HDAC inhibitor; inhibits IFN-α production in PBMCs (EC50 = 8.9 μM); induces hyperacetylation of tubulin (IC50 = 2.9 μM); inhibits LTA4 hydrolase and aminopeptidase activity (IC50s = 15.86 and 11.59 μM, respectively); inhibits 5-LO (IC50 = 27 μM); inhibits the production of LTB4 in neutrophils (IC50 = 12.91 μM) and reduces fMLP-induced neutrophil migration at 50 and 100 μM; reduces neutrophil levels, as well as TNF-α and IL-1β protein levels, in BALF in a mouse model of LPS-induced acute lung injury at 100 mg/kg