Immunohistochemistry (Paraffin): 1:100-1:1000, Western Blot: 1:500-1:3000
Reviews / Ratings
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Description
DDR2 Polyclonal Antibody. Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subcl
Immunogen
n/a
Other Names
MIG20a, NTRKR3, TKT, TYRO10, CD167 antigen-like family member B, cell migration-inducing protein 20, discoidin domain receptor 2, discoidin domain receptor family, member 2, discoidin domain-containing receptor 2, discoidin domain-containing receptor tyrosine kinase 2, hydroxyaryl-protein