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Description
This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This gene is expressed in several tissues, particularly in colon, trachea and in brain, and the protein participates in colon and neural drug metabolism. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported, but the biological validity and/or full-length nature of some variants have not been determined. Synonyms: Polyclonal CES3 antibody, Anti-CES3 antibody, carboxylesterase 3 antibody, ES31 antibody, FLJ21736 antibody.
Immunogen
CES3 antibody was raised in rabbit using the C terminal of CES3 as the immunogen