Western Blot (WB), Immunofluorescence Microscopy (IF), IHC
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Description
Purified anti-NTAL. Non-T cell activation Linker (NTAL) is a transmembrane adaptor protein with an apparent molecular weight of 30 kD expressed on B cells, natural killer (NK) cells, and myeloid cells. The NTAL protein is found in rafts, which are membrane microdomains that participate in B cell activation. NTAL interacts with a variety of proteins including Grb2, PLC gamma 2, and PLC gamma 1. This gene is one of the contiguous genes at 7q11.23 commonly deleted in Williams syndrome.
Immunogen
Recombinant cytoplasmic domain (91-243 a.a.) of human NTAL.
Other Names
Non-T cell activation linker, linker of activated B cells (LAB), Williams-Beuren syndrome chromosome region 5