MW: 39,743 Da. Purity >95 % as determined by SDS-PAGE. A DNA sequence encoding the extracellular domain (Met 1-Ser 297) of human FCGRT (P55899) was fused with a polyhistidine tag at the C-terminus, constructed the plasmid 1; A DNA sequence encoding the human B2M (P61769) (Met 1-Met 119) constructed the plasmid 2. The two plasmids were co-expressed and the FCGRT / B2M heterodimer was purified.
Size
0.01 mg, 0.02 mg
Concentration
n/a
Applications
The recombinant heterodimer of human FCGRT/B2M comprises 385 (285 + 100) amino acids and has a calculated molecular mass of 43.5 (31.8 + 11.7) kDa. The apparent molecular mass of rh FCGRT/B2M heterodimer is approximately 35 & 12 kDa respectively in SDS-PAGE under reducing conditions.
Other Names
[Heterodimer of IgG receptor FcRn large subunit p51 (alpha chain) (FCGRT) and Beta-2-microglobulin (beta chian, subunit p14) (B2M)]