Purity > 90% as determined by SDS-PAGE. MW: 48.3kDa. Full Length of Mature Protein: 18-416aa. N-terminal 6xHis-tagged. Mus musculus (Mouse). Calcium-binding chaperone that promotes folding, oligomeric assbly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis.
Size
100ug
Concentration
n/a
Applications
RUO
Other Names
CRP55Calregulin; Endoplasmic reticulum resident protein 60; ERp60HACBP