An antibiotic with diverse biological activites; inhibits growth of S. aureus, B. subtilis, M. luteus, M. flavus, B. fragilis, C. difficile, C. perfringens, and P. acnes (MICs = 0.4-12.5 μg/ml); inhibits strand-passing activity of topoisomerase II in a P4 unknotting assay; inhibits protein synthesis in CEFs and 3T6 cells (IC50s = 7 and 70 μM, respectively); cytotoxic to human lung carcinoma A549 cells in vitro (IC50 = 95 nM); increases median survival in P388 leukemia and B16 melanoma mouse tumor models (10 mg/kg per day)