A bacterial metabolite; an AR antagonist that inhibits binding of DHT to ARs (IC50 = 13 μM); inhibits DHT-induced expression of prostate-specific antigen in LNCaP cells (IC50 = 1.75 nM); is cytotoxic to A549, HCT116, and HepG2 cells (IC50s = 34.3, 47, and 37.2 μg/ml, respectively); has nematocidal activity against the pine wood nematode B. xylophilus (LC50 = 0.84 μg/ml); increases survival of P. densiflora trees inoculated with B. xylophilus