An antagonist of NMDA receptors with high affinity for the glycine binding site (Ki = 140 nM) that is functional both in vitro and in vivo; also an agonist of GPR17 (EC50 values range from 7 nM to 6 μM, depending on the assay)
Size
10 mg
Concentration
n/a
Applications
n/a
Other Names
MDL29951 allosteric inhibitor inhibit enzyme fructose 1,6-bisphosphatase FBP1 NMDA receptor antagonist glycine activation in vitro vivo N-methyl-D-aspartate biochemical agonist biochemistry signal transduction neuroscience GPR17 neurorecptor