Intercellular Adhesion Molecule 1 (ICAM1) (Active) protein
Description
ICAMs are members of the Ig superfamily of calcium-independent transmembrane glycoproteins. ICAM-1 is a ligand for lymphocyte function-associated (LFA) and Mac-1 integrins and the major human rhinovirus receptor. The primary function of ICAM-1 is to provide adhesion between endothelial cells and leukocytes after stress or injury. The human ICAM-1 gene codes for a 505 amino acid transmembrane glycoprotein containing a 29 amino acid cytoplasmic domain, a 23 amino acid transmembrane domain, and a 453 amino acid extracellular domain. Recombinant human ICAM-1 is a 49.5 kDa glycoprotein comprising the extracellular domain (453 amino acid residues) of ICAM-1. Alternative Names: major group rhinovirus receptor protein, ICAM1, CD54 antigen protein, ICAM 1, ICAM-1 protein, Intercellular adhesion molecule 1 protein, ICAM-1, ICAM-1 protein, ICAM 1 protein