A FAK inhibitor; selective for FAK over 261 kinases; inhibits FAK autophosphorylation at Y397 in OVCAR8 ovarian, U87MG glioblastoma, and A549 lung cancer cell lines (IC50s = 15, 8.5, and 12 nM, respectively); induces apoptosis, decreases viability (IC50 = 25 μM), and inhibits colony formation in L3.6P1 cells; leads to lower tumor weight and fewer metastases in an orthotopic mouse model of uterine cancer at 75 mg/kg per day