Recombinant Human Brain-derived neurotrophic factor (BDNF), partial
Description
Purity > 90% as determined by SDS-PAGE. MW: 38.5kDa. Partial: 137-237aa. N-terminal GST-tagged. Homo sapiens (Human). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systs. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is phasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.