Insulin-Like Growth Factor 1 (IGF1) protein (His tag)
Description
Human Placenta Growth Factor-1 (PlGF-1), a 19 kDa protein consisting of 131 amino acid residues and fused to a C-terminal His-tag (6x His), is produced as a homodimer. Human Placenta Growth Factor (PlGF) is a polypeptide growth factor and a member of the platelet-derived growth factor family but more related to vascular endothelial growth factor (VEGF). PlGF-1 acts only as a very weak mitogen for some endothelial cell types and as a potent chemoattractant for monocytes. The physiological function in vivo is still controversal. In several reports it was shown not to be a potent mitogen for endotehlial cells and not angiogenic in vivo by using different assays. Alternative Names: PGF protein, Placenta Growth Factor-1 protein, PIGF-1 protein, PIGF 1, PIGF-1, PIGF protein, PIGF 1 protein, PIGF1