A PAD inhibitor; a modified version of Cl-amidine; irreversibly inactivates all four PAD subtypes (kinact/KI = 16,100, 4,100, 6,800, and 13,300 M-1min-1 for PAD1-4, respectively); potency is increased 20-fold over that of Cl-amidine (EC50 = 8.8 μM versus >200 μM for Cl-amidine); longer half-life than Cl-amidine (1.75 h versus ~15 min, respectively); inhibits formation of neutrophil extracellular traps
Size
5 mg
Concentration
n/a
Applications
n/a
Other Names
PAD 4 postraslational BBCl NET Peptidylarginine Deiminase 4