bovine, canine, equine, human, mouse, porcine, rabbit, rat
Isotype
n/a
Format
purified
Size
100 μl
Concentration
n/a
Applications
Immunocytochemistry: 4 μg/mL, Immunofluorescence: Assay-Dependent, Immunohistochemistry: Assay-Dependent, Western Blot: 1:1000
Reviews / Ratings
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Description
USP9X Polyclonal Antibody. USP9X is an ubiquitin-specific protease involved in the removal and recycling of ubiquitin from proteins degraded in proteasomes. As a deubiquitinating enzyme, USP9x has a critical function in tight junction biogenesis by controlling the levels of the exchange factor for Arf6 (EFA6), a protein shown to facilitate tight junction formation during a narrow temporal window preceding the establishment of cell polarity (1). USP9X is also located on the X-chromosome but escapes X-inactivation, and defects in USP9X may cause gonadal degeneration in Turner syndrome.
Immunogen
n/a
Other Names
Ubiquitin specific peptidase 9, X-linked, DFFRX, FAF, FAM