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| Antigenic Specificity | Cytokeratin 20 |
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| Clone | RM283 |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | purified |
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| Size | 100 μl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 1:100-1:250, Western Blot: 1:1000-1:2000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Cytokeratin 20 Monoclonal Antibody (RM283). CK20 is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This cytokeratin is a major cellular protein of mature enterocytes and goblet cells and is specifically expressed in the gastric and intestinal mucosa. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21. CK20 plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin |
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| Immunogen | n/a |
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| Other Names | n/a |
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| Gene, Accession # | Entrez: 54474; Uniprot: P35900 |
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| Catalog # | MA5-27906 |
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| Price | |
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| Order / More Info | Cytokeratin 20 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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