| Edit |   |
|---|
| Antigenic Specificity | Cytokeratin 8 |
|---|
| Clone | 8A5D12 |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG1 |
|---|
| Format | purified |
|---|
| Size | 100 μL |
|---|
| Concentration | n/a |
|---|
| Applications | Immunocytochemistry: 1:200-1:1000, Immunofluorescence: 1/200 - 1/1000, Immunohistochemistry: 1/200 - 1/1000, Western Blot: 1/500 - 1/2000 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Cytokeratin 8 Monoclonal Antibody (8A5D12). This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. |
|---|
| Immunogen | n/a |
|---|
| Other Names | K8; KO; CK8; CYK8; K2C8; CARD2; KRT8 |
|---|
| Gene, Accession # | Entrez: 3856; Uniprot: P05787 |
|---|
| Catalog # | MA5-15460 |
|---|
| Price | |
|---|
| Order / More Info | Cytokeratin 8 Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | PubMed: 25222612 |
|---|