A Cdk2 inhibitor (IC50 = 0.41 μM) that demonstrates 10- to 36-fold selectivity against Cdk2-cyclin A compared to Cdk1-cyclin B, Cdk4-cyclin D, Cdk5-p25, or Cdk7-cyclin H; induces cell-cycle arrest at the G2-M phase
Size
500 μg
Concentration
n/a
Applications
n/a
Other Names
inhibitor cyclin-dependent kinase 2 Cdk2 cell-cycle arrest antiproliferation apoptosis cancer biochemical protein inhibit NU6140 cyclinA A G2M G2-M paclitaxel HeLa anti-apoptotic survivin