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Description
PDGFRA Polyclonal Antibody. PDGFR (Platelet Derived Growth Factor Receptor) exhibits two different isoforms, alpha and beta; coded by two different genes. They possess five immunoglobulin like domains that are involved in ligand binding. Two tyrosine kinase domains are separated by a kinase insert to which PI-3 kinase can bind. PDGF AA can bind autophosphorylate and activate only PDGFR, alpha while PDGF BB can bind and activate to both PDGFR, alpha; and beta;.
Immunogen
n/a
Other Names
PDGF A-chain, PDGF subunit A, PDGF-1, platelet-derived growth factor A chain, platelet-derived growth factor alpha chain, platelet-derived growth factor alpha isoform 2 preproprotein, platelet-derived growth factor subunit A, pdgfr-a