goat, human, mouse, nonhuman primate, ovine, rabbit, rat
Isotype
IgG2b
Format
purified
Size
500 ug
Concentration
n/a
Applications
ELISA: 1:64000, Immunohistochemistry: 1-10 μg/mL, Western Blot: 1-10 μg/mL
Reviews / Ratings
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Description
MBP Monoclonal Antibody. The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called Golli-MBP) that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The sec