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Description
Mouse Anti-MBD2 Recombinant Antibody (CBFYM-1799). This product is mouse antibody that recognizes MBD2. The antibody CBFYM-1799 can be used for immunoassay techniques such as: WB, IP, IF, IHC-P, ELISA. DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain. Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. The protein encoded by this gene may function as a mediator of the biological consequence
Immunogen
n/a
Other Names
Methyl-CpG Binding Domain Protein 2; Demethylase; DMTase; Methyl-CpG-Binding Domain Protein 2; Methyl-CpG-Binding Protein MBD2; NY-CO-41