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Description
Recombinant Mouse Anti-CD46 Antibody scFv Fragment (SC1.N122). The product is a novel CD46 modulator that effectively targets cancer stem cell and may be used to treat patients suffering from a wide variety of malignancies. The data show that SC1.N122 is a pan-CD46 antibody, as it bound to CD46 exons 1-6, CD46D-His, ELISA, Flow Cytometry
Immunogen
Both the recombinant fusion protein comprising the extracellular portion of CD46-D-His and two synthetic peptides derived from the CD46 protein sequence and located within the exon-exon junctions of exons 6-8 and 6-9
Other Names
CD46 Molecule, Complement Regulatory Protein; Membrane Cofactor Protein (CD46, Trophoblast-Lymphocyte Cross-Reactive Antigen); Antigen Identified By Monoclonal Antibody TRA-2-10; CD46 Antigen, Complement Regulatory Protein; Trophoblast Leukocyte Common An