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Description
Rabbit IgG polyclonal Picoband? antibody for Tryptophan Hydroxylase detection. Tested with WB, Direct ELISA in Human;Mouse;Rat. No cross reactivity with other proteins. Tryptophan hydroxylase 1 (TPH1) is an isoenzyme of tryptophan hydroxylase which in humans is encoded by the TPH1 gene. This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.
Immunogen
E. coli-derived human Tryptophan Hydroxylase recombinant protein (Position: M1-K111).