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Description
FOXN1 Polyclonal Antibody, Biotin Conjugated. ? Target Background: Mutations in the winged-helix transcription factor gene at the nude locus in mice and rats produce the pleiotropic phenotype of hairlessness and athymia, resulting in a severely compromised immune system. This gene is orthologous to the mouse and rat genes and encodes a similar DNA-binding transcription factor that is thought to regulate keratin gene expression. A mutation in this gene has been correlated with T-cell immunodeficiency, the skin disorder congenital alopecia, and nail dystrophy. Al
Immunogen
KLH conjugated synthetic peptide derived from human FOXN1. Immunogen Range: 350-400/648