產(chǎn)品名稱(chēng) PEN2 Antibody from INVITROGEN ANTIBODIES
    產(chǎn)品貨號(hào) PA3-16762
    產(chǎn)品價(jià)格 現(xiàn)貨詢(xún)價(jià)，電話(huà)：010-67529703
    產(chǎn)品規(guī)格 100 μL
    產(chǎn)品品牌 INVITROGEN ANTIBODIES
    產(chǎn)品概述
    產(chǎn)品詳情
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    Antigenic SpecificityPEN2
    Clonepolyclonal
    Host SpeciesRabbit
    Reactive Specieshuman, mouse
    Isotypen/a
    Formatpurified
    Size100 μL
    Concentrationn/a
    ApplicationsImmunoprecipitation: 1:50-1:100, Western Blot: 1:1000-1:2500
    Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
    DescriptionPEN2 Polyclonal Antibody. Presnilin (PS1/PS2) complexes are responsible for the intramembrane gamma-secretase cleavage of the beta-amyloid precursor protein. Presenilin enhancer 2 (PEN2) is an essential cofactor involved physically interacting with PS1 and is necessary for gamma-secretase activity. Endogenous PEN2 preferentially interacts with PS1 holoprotein. Down-regulation of PEN2 expression abolishes the endoproteolysis of PS1 and overexpression promotes the production of PS1 fragments.
    Immunogenn/a
    Other NamesGamma-secretase subunit PEN-2, hematopoietic stem/progenitor cells protein MDS033, MDS033, MSTP064, presenilin enhancer 2, Presenilin enhancer protein
    Gene, Accession #Entrez: 55851, 66340; Uniprot: Q9CQR7, Q9NZ42
    Catalog #PA3-16762
    Price
    Order / More InfoPEN2 Antibody from INVITROGEN ANTIBODIES
    Product Specific Referencesn/a
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