Angiotensin I (human, rat, mouse) (trifluoroacetate salt)
Description
A peptide; is converted to the vasoconstrictor angiotensin II by ACE; binds to angiotensin receptors in human myometrium membrane preparations (Kd = 11.2 nM); increases the renal vascular resistance in isolated rat kidney (EC50 = 10.5 nM); increases MAP and plasma AVP level in fetal ewes (5 μg/kg, i.c.v.)