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Description
Function: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.Subcellular location: Cell membrane, Multi-pass membrane protein. Also known as: 5-hydroxytryptamine receptor 1E, 5-HT-1E, 5-HT1E, Serotonin receptor 1E, S31.
Immunogen
A synthetic peptide from c-terminal region of human 5HT1E receptor (Serotonin receptor 1E) conjugated to an immunogenic carrier protein was used as the antigen.