Ustekinumab is a fully human monoclonal antibody that binds with high specificity and affinity to the cytokines interleukin (IL)-12 and IL-23, thereby suppressing IL-12- and IL-23-mediated inflammation associated with psoriasis. Ustekinumab (STELARA?) is the only FDA-approved medicine that targets IL-12 and IL-23, which are thought to be associated with gastrointestinal inflammation in Crohn's disease. BioSim Ustekinumab (Stelara?) ELISA Kit is a sandwich based ELISA kit. Standards and samples are incubated in the microtitre plate coated with the reactant for Ustekinumab (Stelara?). After incubation, the wells are washed. HRP-conjugated probe is added and binds to ustekinumab captured by the reactant on the surface of the wells.
Size
96 Assays
Concentration
n/a
Applications
Sensitivity: 3 ng/ml,Detection Range: 3 - 100 ng/ml,This ELISA kit is used for in vitro quantitative determination of Ustekinumab,Recovery rate: 85 - 115% with normal human serum samples with known concentrations,Cross Reactivity: No significant cross-reactivity or interference with other proteins present in native human serum or other therapeutic immunoglobulins.,Assay Precision: Intra-Assay: CV < 15%; Inter-Assay: CV < 15% (CV (%) = SD/mean X 100)