Vedolizumab is a recombinant humanized IgG1 monoclonal antibody directed against the human lymphocyte α4β7 integrin, a key mediator of gastrointestinal inflammation. It is used in the treatment of moderate to severe active ulcerative colitis and Crohn's disease for patients who have had an inadequate response with, lost response to, or were intolerant to inhibitors of tumor necrosis factor-alpha (TNF-alpha) or other conventional therapies. BioSim? Vedolizumab ELISA kit is a Solid phase enzyme-linked immunosorbent assay (ELISA) based on the sandwich principle. Standards and samples (serum or plasma) are incubated in the microtitre plate coated with the reactant for Vedolizumab (Cyramza?). After incubation, the wells are
Size
96 assays
Concentration
n/a
Applications
Sensitivity: 30 ng/ml,Recovery rate: 85 - 115% with normal human serum samples with known concentrations,Detection Range: 30 - 1000 ng/ml,This ELISA kit is used for in vitro quantitative determination of Vedolizumab,Cross Reactivity: Except for Vedolizumab, there is no cross reaction with other therapeutic antibodies and native serum immunoglobins,Assay Precision: Intra-Assay: CV < 15%; Inter-Assay: CV < 15% (CV (%) = SD/mean X 100)