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Description
Histone methyltransferase. Methylates 'Lys-9' of histone H3 (in vitro). H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. During G0 phase, it probably contributes to silencing of MYC- and E2F-responsive genes, suggesting a role in G0/G1 transition in cell cycle. Synonyms: Monoclonal EHMT1 antibody, Anti-EHMT1 antibody, GLP antibody, FP13812 antibody, FLJ12879 antibody, KIAA1876 antibody, EUHMTASE1 antibody, Eu-HMTase1 antibody, bA188C12.1 antibody, DKFZp667M072 antibody, RP11-188C12.1 antibody.
Immunogen
EHMT1 antibody was raised in mouse using recombinant Homosapienseuchromatichistone-Lysinen-Methyltransferase1