MW: 18,432 Da. Purity >85 % as determined by SDS-PAGE. Background: TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM). TIGIT is expressed on regulatory, memory, activated T cells and NK cells. It binds PVR with high affinity, and PVRL2 with lower affi
Size
0.02 mg, 0.05 mg
Concentration
n/a
Applications
The secreted recombinant human TIGIT comprises 128 amino acids with a predicted molecular mass of 14.2 kDa.