A competitive transition-state substrate analog inhibitor of DPP IV (Ki = 126 nM); used to improve glucose tolerance, insulin sensitivity, and β-cell glucose responsiveness in diabetic rat models at 20 mg/kg/day
Size
10 mg
Concentration
n/a
Applications
n/a
Other Names
136259-20-6 335149-?22-?9 DPP-4 dipeptidyl peptidase DPP IV inhibitor type 2 diabetes insulin resistance biochemical two glucose-dependent insulinotropic polypeptide GIP glucagon-like peptide 1 GLP-1 GLP1 DPPIV DPP4 nutrient-stimulated secretion circulating enzyme experimental antidiabetic agent P3298 P32-98 competitive transition-state substrate analog tolerance sensitivity β-cell responsiveness diabetic rat model inhibit