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Description
Rabbit IgG polyclonal antibody for human HP1 alpha (Heterochromatin protein 1 homolog alpha).tested for IF, IHC, WB in Human. HP1 alpha is a component of heterochromatin. It recognizes and binds to histone H3 tails methylated at '?Lys-9', leading to epigenetic repression of transcription. HP1 alpha may also interact with lamin B receptor (LBR), thereby contributing to the association of the heterochromatin with the inner nuclear membrane. Further, HP1 alpha is involved in the formation of a functional kinetochore through interaction with MIS12 complex proteins.
Immunogen
This antibody is raised in rabbit against human HP1?? (Heterochromatin protein 1 homolog alpha), using the full length recombinant GST tagged protein.
Other Names
Chromobox protein homolog 5;Antigen p25;Heterochromatin protein 1 homolog alpha;HP1 alpha;CBX5;HP1A;