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Description
Polyclonal Antibody to detect H3 Pan in human samples. Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Histone tails undergo numerous post-translational modifications, which either directly or indirectly alter chromatin structure to facilitate transcriptional activation or repression or other nuclear processes. In addition to the genetic code, combinations of the different histone modifications reveal the so-called ``histone code''. Histone methylation and demethylation is dynamically regulated by respectively histone methyl transferases and hist
Immunogen
KLH-conjugated synthetic peptide of Histone H3 containing an unmodified sequence from the central part and from the C-terminus of histone H3.