Purity: > 90% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 20% glycerol,1mM DTT . rRNA-processing protein uTP23 homolog, also known as uTP23, is a small subunit (SSu) processome component. The SSu processome is a complex involved in ribosome biogenesis and is required for pre-18S rRNA maturation. uTP23 is required for the first three cleavage steps in 18S rRNA maturation. In addition, single-point mutations in the conserved putative active site of utp24 but not utp23 abrogate its function in ribosome biogenesis. Recombinant human uTP23 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.