Immunohistochemistry (Paraffin): 1:100-1:1000, Western Blot: 1:500-1:3000
Reviews / Ratings
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Description
FCAR Polyclonal Antibody. This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Immunogen
n/a
Other Names
CD89, Fc alpha receptor, IgA Fc receptor, immunoglobulin alpha Fc receptor