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Description
FCAR Polyclonal Antibody. Fc (Ig constant fragment) receptors ensure protection of the host against foreign antigens, such as microorganisms and pathogens, by removing Ig-coated antigen complexes from circulation. Fc receptors are present on lymphoid and myeloid derivatives, where they mediate endocytosis of Ig-antigen complexes, antibody production in B cells through T cell antigen presentation, cytotoxicity, and the release of cytokines and reactive oxygen species. Human myeloid receptor for the Fc fragment of IgA (CD89) is a glycoprotein that is expressed on the surface of neutrophils, monocytes, macrophages and eosinophils and is a potent cytotoxic trigger molecule. Cytokines can initiate a highbinding state for CD89 through a mechanism
Immunogen
n/a
Other Names
Immunoglobulin alpha Fc receptor; IgA Fc receptor; FCAR; CD89