Highly Purified (~90%). Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). PGP is an essential intermediate in the biosynthetic pathway of cardiolipin, a mitochondrial-specific phospholipid regulating the membrane integrity and activities of the organelle. Has also been shown to display phosphatase activity toward phosphoprotein substrates, specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production. Has probably a preference for proteins phosphorylated on Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues. Probably involved in regulation of insulin secretion in pancreatic beta cells (By similarity) Source: Recombinant protein corresponding to aa2-201 from human PTPMT1, fused to GST-tag at N-terminal, expressed in Sf9 insect cells. Molecular Weight: ~49.3kD Applications: Suitable for use as an immunogen, in binding assays or as an antigen in autoimm