Capping Protein (Actin Filament), Gelsolin-Like (CAPG) (AA 1-348) protein
Description
Macrophage-capping protein, also known as CAPG, belongs to the gelsolin/villin family of actin-regulatory proteins. CAPG is a calcium-sensitive DNA-binding protein that plays a role in macrophage function. It is expressed in macrophages and macrophage-like cells and can localize both to the nucleus and the cytoplasm. This protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. Recombinant human CAPG was expressed in E. coli and purified by using conventional chromatography techniques. Alternative Names: Capping protein gelsolin like protein, Myc basic motif homolog 1., Actin regulatory protein CAP G protein, gCap39 protein, MCP protein, CAPG protein, Macrophage capping protein protein, mbh1 protein, Gelsolin like capping protein protein, AFCP protein, Macrophage-capping protein Actin capping protein GCAP39 protein, Capping protein (actin filament) gelsolin like protein