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Description
Rabbit Anti-TIA1 Recombinant Antibody (CBYJT-3104). Provided herein is a Rabbit monoclonal antibody, which binds to TIA1 (TIA1 Cytotoxic Granule Associated RNA Binding Protein). The antibody can be used for immunoassay techniques, such as WB, IP, IHC-P, ICC. TIA1 is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing.
Immunogen
Synthetic peptide within Human TIA1 aa 350 to the C-terminus (C terminal). The exact sequence is proprietary.