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Description
HRH1 Polyclonal Antibody. The histamine H1 receptor has been reported to be expressed in brain, kidney, lung, nasal cavity, placenta, skeletal and smooth muscle, synovium, and vessel. ESTs have been isolated from B-cell/lung/testis, brain, heart, liver/spleen, and lung libraries G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist. All GPCRs share a structural motif consisting of seven membrane-spanning helices, and exist in both active and inactive forms. An array of activating ligands participate in the conformation of GPCRs which leads to signaling via G-proteins and downstream effectors. Ongoing studies have also shown the vast seri